Email

bchadwick@um.edu.mo

Tel

+853 8822 9284

Office

N22-1016

Consultation Hours

Wed: 11:00-12:00
Thu: 11:00-12:00

Benjamin James CHADWICK

Assistant Professor

Academic Qualifications

• BSc, University of Delaware
• PhD, University of Georgia
• Postdoctoral fellow, University of Wisconsin-Madison

Research Interests

• Human fungal pathogenesis
• Antifungal drug resistance
• Medicinal fungi

  1. Chadwick BJ, Ristow L, Blackburn E, Xie X, Krysan D, Lin X. Microevolution of Cryptococcus neoformans in high CO2 converges on mutations isolated from patients with relapsed cryptococcosis. Cell Reports. 44(3) (2025)
  2. Chadwick BJ, Xie X, Ristow L, Krysan D, Lin X. Discovery of CO2 tolerance genes associated with virulence in the fungal pathogen Cryptococcus neoformans. Nature Microbiology, 9, pages2684–2695 (2024)
  3. Chadwick BJ, Lin X. Effects of CO2 in fungi. Curr Opin Microbiol. 2024 Jun;79:102488.
  4. Li Yeqi, Chadwick BJ, Pham T, Xie X, Lin X. Aspartyl peptidase May1 induces host inflammatory response by altering cell wall composition in the fungal pathogen Cryptococcus neoformans. mBio. 15:e00920-24.
  5. Ristow L, Jezewski A, Chadwick BJ, Stamnes M, Lin X, Krysan D. The fungal pathogen Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetry. Nature Communications 14, 6587 (2023). https://doi.org/10.1038/s41467-023-42318-y
  6. Chadwick BJ, Ross BE, Lin X. Molecular Dissection of Crz1 and Its Dynamic Subcellular Localization in Cryptococcus neoformans. Journal of Fungi. 2023; 9(2):252. https://doi.org/10.3390/jof9020252
  7. Chadwick BJ, Pham T, Xie X, Ristow L, Krysan D, Lin X. The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformans. eLife, 11, e82563. doi:10.7554/eLife.82563
  8. Chadwick BJ, Lin X. On the history and applications of congenic Strains in Cryptococcus research. Pathogens. 2020 Sep 15;9(9):750. doi: 10.3390/pathogens9090750

  1. Morgridge Institute Postdoc Fellowship, University of Wisconsin-Madison, 2024
  2. Excellence for In-Vivo Research Award, Marine Biological Laboratory (MBL)