Zhangfeng ZHONG 鍾章鋒

Representative peer-reviewed journal papers (h-index 43)

[1] Shi R, Tan W, Jin H, Chan S, Li W, Lei S, Cui G, Wang Y, Yang D, Zhong Z. MicroRNA-enriched Plant-derived Exosomes Alleviates Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota. Adv Sci. 2025, 12:e05921.

[2] S Chen, C Shen, W Li, Y Fan, DH Yang, Y Wang, R Feng, G Li, Z Zhong. Recent Advances in Bioactivity-Guided Drug Screening Strategies for Pre-Clinical and Clinical Drug Discovery. Trends Analyt Chem. 2024, 181: 118042.

[3] Zhu Y, Fang Y, Su L, Li X, Guo P, Duan J, Ran K, Huang N, Chen X, Chen X, Liu Y, Zhong Z*, Zhang C*, Zhang J*. Difluoroboron curcumin/glycyrrhizic acid liposome-incorporated Mg²⁺-chelated microgel for MRSA-infected wound photothermal therapy. Drug Resist Updat. 2026, 85:101347.

[4] Zheng W, Chen J, Liu J, Han X, Zhang S, Yang C, Yu H, Tan W, Zhong Z. Unveiling the potential of natural TLR modulators in cancer immunotherapy. Pharmacol Res. 2025, 221:107969.

[5] Yang C, Wang K, Liang Q, Tian TT, Zhong Z. Role of NSD1 as potential therapeutic target in tumor. Pharmacol Res. 2021, 173:105888.

[6] Han X, Zheng W, Sun Z, Luo T, Li Z, Lai W, Jing M, Kuang M, Su H, Tan W, Zhong Z. Plant-derived exosomes: Unveiling the similarities and disparities between conventional extract and innovative form. Phytomedicine. 2025, 145:157087.

[7] Shi R, Chan SI, Jin H, Li W, Zhang L, Yang J, Wang R, Zheng X, Cui G, Zhong Z. Jiegeng Gancao Decoction Ameliorates Ulcerative Colitis: An Integrative Approach Combining Network Pharmacology and Proteomics via in silico and in vivo studies. Phytomedicine. 2025, 145:156972.

[8] Huang J, Shi R, Chen F, Tan HY, Zheng J, Wang N, Li R, Wang Y, Yang T, Feng Y, Zhong Z. Exploring the anti-hepatocellular carcinoma effects of Xianglian Pill: Integrating network pharmacology and RNA sequencing via in silico and in vitro studies. Phytomedicine. 2024, 133:155905.

[9] Zhu Z, Cui L, Yang J, Vong CT, Hu Y, Xiao J, Chan G, He Z, Zhong Z. Anticancer effects of asiatic acid against doxorubicin-resistant breast cancer cells via an AMPK-dependent pathway in vitro. Phytomedicine. 2021, 92:153737.

[10] Cui D, Qiao W, Chen W, Li P, Wang S, Wang Y, Liao F, Li F, Wang K, Wang Y, Su H, Zhong Z. Anti-tumor immunotherapy of Scutellaria baicalensis-derived vesicles on immune checkpoint modulation in colorectal cancer. Aging Dis. 2026, in press.

[11] Chan KI, Zhang S, Li G, Xu Y, Cui L, Wang Y, Su H, Tan W, Zhong Z. MYC Oncogene: A Druggable Target for Treating Cancers with Natural Products. Aging Dis. 2024, 15:640.

[12] Shi R^#, Zhong Z^#, Wang L, Mao Y, Tang Y, Wang Y, Wei J, Xie B*, Li P*. Assembly of peptide guided precise accumulation and retention of nano-herb medicine for enhanced immunotherapy of colorectal cancer. Chin Chem Let. 2025, in press.

[13] Yang C, Li D, Zang S, Zhou Y, Zhang L, Zhong Z. Nanocoating of CsgA protein for enhanced cell adhesion and proliferation. Chin Chem Let. 2023, 34: 107733.

[14] Chen W, Fang D, Zhang L, Kuang M, Zhang M, Shen C, Liu Y, Zhou H, Wang S, Zhao W, Wang Y, Zhong Z. Rosa Roxburghii Tratt Fruit Juice Ameliorates DSS-Induced Colitis by Repairing Intestinal Mucosal Barrier Function and Regulating Gut Microbiota in a Way Independent of Vitamin C. eFood, 2025, 6: e70084.

[15] Chan S, Xiong P, Zhao M, Zhang S, Zheng R, Ye J, Chan K, Li C, Zhong Z. Anti-inflammatory effects of natural products from vitamin C-rich fruits. Food Frontiers. 2024, 5: 2383.

[16] Cui D, Zhang C, Zhang L, Zheng J, Wang J, He L, Jin H, Kang Q, Zhang Y, Li N, Sun Z, Zheng W, Wei J, Zhang S, Feng Y, Tan W, Zhong Z. Natural anti-cancer products: insights from herbal medicine. Chin Med. 2025, 20:82.

[17] Zhong Z, Yu H, Wang S, Wang Y, and Cui L. Anti-cancer effects of Rhizoma Curcumae against doxorubicin-resistant breast cancer cells. Chin Med. 2018, 13:44.

[18] Zhong Z, Vong CT, Chen F, Tan H, Zhang C, Wang N, Cui L, Wang Y, Feng Y. Immunomodulatory potential of natural products from herbal medicines as immune checkpoints inhibitors: helping to fight against cancer via multiple targets. Med Res Rev. 2022, 42:1246.

[19] Zhong Z, Qiang W, Wang C, Tan W, and Wang Y. Furanodiene enhances the anti-cancer effects of doxorubicin on ERα-negative breast cancer cells in vitro. Eur J Pharmacol. 2016, 774:10.

[20] Zhong Z, Tan W, Chen X, and Wang Y. Furanodiene, a natural small molecule suppressed metastatic breast cancer cell migration and invasion. Eur J Pharmacol. 2014, 737:1.

[21] Zhong Z, Chen X, Tan W, Xu Z, Zhou K, Wu T, Cui L, and Wang Y. Germacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis. Eur J Pharmacol. 2011, 667:50.

[22] Guan X, Zheng X, Vong C, Zhao J, Xiao J, Wang Y, Zhong Z. Combined effects of berberine and evodiamine on colorectal cancer cells and cardiomyocytes in vitro. Eur J Pharmacol. 2020, 25:173031.

[23] Li D^#, Zhong Z^#, Ko CN, Tian T, Yang C. From mundane to classic: Sinomenine as a multi-therapeutic agent. Br J Pharmacol. 2025, 182:2159.

[24] Zhang C, Wang N, Tan HY, Guo W, Chen F, Zhong Z, Man K, Tsao SW, Lao L, Feng Y. Direct inhibition of the TLR4/MyD88 pathway by geniposide suppresses HIF-1α-independent VEGF expression and angiogenesis in hepatocellular carcinoma. Br J Pharmacol. 2020, 177:3240

[25] Huang Y, Chen C, Su M, Ye W, Wei S, Long K, Huang Y, Chen H, Zhong Z, Hou L, Zhang J, Tan W, Li F. TMEM11 promotes cisplatin resistance by inhibiting BNIP3-mediated mitophagy in bladder cancer. Cancer Lett. 2026, 641:218271.

[26] Tan HY, Wang N, Chan YT, Zhang C, Guo W, Chen F, Zhong Z, Li S, Feng Y. ID1 overexpression increases gefitinib sensitivity in non-small cell lung cancer by activating RIP3/MLKL-dependent necroptosis. Cancer Lett. 2020, 475:109

[27] Huang Y, Chen C, Su M, Li D, Zhang J, Long K, Nie W, Wei S, Chen W, Chen H, Zhong Z, Hou L, Tan W, Li F. MCUB Inhibits PRKN-Dependent Mitophagic Degradation of PD-L1 to Promote Immune Evasion in Bladder Cancer. Adv Sci. 2026, 13:e14764.

[28] Wang K, Xie CJ, Ding Z, Shan T, Zhong Z, Yuan FL, Wu JJ, Yuan ZD, Qian C, Yu L, Liu Y, Cheng J, Zhang QL, Liu W, Zhao Y, Huang J, Zhang WZ, Yin Q, Gao BY, Hou JQ, Wang JC, Mei J, Deng C. PDE5A+ cancer-associated fibroblasts enhance immune suppression in gastric cancer. GUT, 2026, 75:486.